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News Center / News / Zeyad Thonnoon DawoodAl-Rassam has discussed his thesis and he gets many conclusions


Zeyad Thonnoon DawoodAl-Rassam has discussed his thesis and he gets many conclusions
2014-02-19 10:02:38

Zeyad Thonnoon DawoodAl-Rassam has discussed his  thesis entitled: Detection of Some Human Viruses In Patients With Periodontitis and he gets many conclusions

Conclusions:

1majority of chronic periodontitis The was concentrated in middle age, males showed infection more than females.

 Nested PCR assay showed detection of EBV, HSV and CMV in chronic periodontitis as a single and co-infection

3There was no significant association between type of virus detected (EBV, CMV and HSV) with gender, age groups and periodontal Pocket depth.

4Detection of viruses using serum ELISA IgM, IgG kits showed variable results.

 Salivary sIgA level showed a significant increase in chronic periodontitis patients.

 Serum TNF-α showed a significant correlation with serum IL-6 and IL-1β  levels, whereas salivary total protein levels showed a significant negative correlation with salivary peroxidase specific activity . 

 In viral detection periodontitis group, patients with EBV-CMV co infection showed a significant increase in serum I

-L-1β, IFN-ɣ, salivary sIgA and total proteins level.

 Serum IL-6, IL-8 and salivary total proteins levels showed no significant association with age and pocket depth in three study groups.

 Serum IL-1β, IFN-ɣ, TNF-α  and salivary sIgA levels showed a significant increase in ≥ 70 year age group within chronic periodontitis and non-viral detected chronic periodontitis patients groups. However, serum IFN-ɣ showed a significant increase in 60-69 year age group in viral detection periodontitis patients group.

 Salivary sIgA showed a significant increase in patients with 7mm pocket depth in three study groups. However IL-1β and IFN-ɣ levels and salivary peroxidase specific activity showed a significant increase in patients with pocket depth 7mm among different groups.

 


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